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DNA Replication: The Regulatory Mechanisms

  • Conference proceedings
  • © 1992

Overview

Editors:
  1. Patrick Hughes

    1. Institut Jacques Monod, CNRS, Université Paris 7, Paris Cedex 05, France

  2. Ellen Fanning

    1. Institut für Biochemie, München 2, Germany

  3. Masamichi Kohiyama

    1. Institut Jacques Monod, CNRS, Université Paris 7, Paris Cedex 05, France

  • 3900 Accesses

  • 13 Citations

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About this book

DNA replication is a key event in the cell cycle. Although our knowledge is far from complete and many elusive regulatory mechanisms still remain beyondour grasp, many enzymes and a multiplicity of biochemical mechanisms involved have been discovered. Recent findings in E. coli have confirmed and yet surpassed the original hypothesis of F. Jacob. In yeast and higher eucaryotes, the apparent redundancy in putative origins and initiators has made an estimation of the importance of each identified element difficult to access. In spite of well established methodologies - which are also described in the book - the origin identification in mammalian chromosomes is still a controversial subject. On the other hand, considerable advances have been made in our understanding of virus DNA replication and this continues to deepen and broaden our understanding of the controls of cellular DNA replication.

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Table of contents (35 papers)

  1. Front Matter

    Pages I-XX
    Download chapter PDF

  2. Introduction

    1. Regulation of Initiation of Chromosome Replication

      • Arthur Kornberg
      Pages 1-10

  3. Cellular DNA Replication

    1. Cell cycle control of DNA replication

      1. <i>Escherichia coli</i> Strains in Which the Chromosome Is Replicated from Origins Other than <i>oriC</i>
        • Rolf Bernander, Santanu Dasgupta, Kurt Nordström
        Pages 11-21
      2. Dam Methyltransferase in <i>Escherichia coli</i>: Effects of Different Enzymatic Levels on DNA Replication and Cell Growth
        • Erik Boye, Anita Lyngstadaas, Anders Løbner-Olesen
        Pages 23-35
      3. Further Characterization of a DNA Replication Inhibitor from the Cell Membrane of <i>Escherichia coli</i>
        • Patrick Hughes, Abderrahim Malki, John Herrick, Renée Kern, Masamichi Kohiyama
        Pages 37-48
      4. The Involvement of cdc2 in Cell Cycle Control of DNA Replication in Xenopus Egg Extracts
        • J. Julian Blow, Paul Nurse
        Pages 49-58
      5. A Gene of <i>Saccharomyces cerevisiae</i> Probably Involved in the Coordination of Chromatin Replication and Cell Division
        • Ulrike Wintersberger, Anneliese Karwan
        Pages 59-71

    2. Origin identification in mammalian chromosomes

      1. Origins of DNA Replication and Nucleosome Segregation in Mammalian Chromosomes
        • William C. Burhans, Lyubomir T. Vassilev, Jiarui Wu, José M. Sogo, Ferez S. Nallaseth, Melvin L. DePamphilis
        Pages 73-82
      2. Directions of DNA Replication in Yeast and Mammalian Cells
        • Joel A. Huberman, Dharani D. Dubey, Kevin A. Nawotka, George Russev, J. Aquiles Sanchez, Yeup Yoon et al.
        Pages 83-95
      3. The Curious Case of the Novel 2-D Gel Artifact
        • Bonita J. Brewer
        Pages 97-106

    3. Origin structure. function and modification

      1. Structural and Functional Characteristics of Autonomously Replicating Mammalian Origin-Enriched Sequences (<u>ORS</u>)
        • M. Zannis-Hadjopoulos, C. E. Pearson, D. Bell, D. Mah, M. McAlear, G. B. Price
        Pages 107-116
      2. Mutations Affecting Replication Origin Function in Yeast
        • Stephen E. Kearsey, David Kipling
        Pages 117-127
      3. Role of Transcriptional Elements in Activating Origins of Replication
        • Zong-Sheng Guo, Maria Wiekowski, Sadhan Majumder, Miriam Miranda, Melvin L. DePamphilis
        Pages 129-138
      4. Telomere Replication in <i>Saccharomyces cerevisiae</i>
        • V. A. Zakian, S.-S. Wang, R. Wellinger
        Pages 139-150

    4. Initiator — replication origin recognition

      1. The Role of DnaA-DnaA Box Interaction in Initiation of Chromosomal Replication in <i>Bacillus subtilis</i>
        • N. Ogasawara, S. Moriya, H. Yoshikawa
        Pages 151-160
      2. DnaA Protein Mediated Transcription Termination in the GUA Operon of <i>Escherichia coli</i>
        • Christoph Schaefer, Andreas Holz, Walter Messer
        Pages 161-168
      3. Screens for Proteins Binding to the ARS Consensus Sequence
        • James F. Theis, Carol S. Newlon
        Pages 169-179
      4. Protein-DNA Interaction at Yeast Replication Origins: an ARS Consensus Binding Protein
        • J. F. X. Hofmann, S. M. Gasser
        Pages 181-191
      5. Genetic Analysis of the Roles of Yeast ARS Binding Factor I
        • P. R. Rhode, J. L. Campbell
        Pages 193-204
      6. Proteins Involved in ARS Function in Yeast
        • B. K. Tye, V. Chang, C. Christ, R. Elble, S. Gibson, S. Passmore et al.
        Pages 205-213
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Editors and Affiliations

  • Institut Jacques Monod, CNRS, Université Paris 7, Paris Cedex 05, France

    Patrick Hughes, Masamichi Kohiyama

  • Institut für Biochemie, München 2, Germany

    Ellen Fanning

Accessibility Information

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Bibliographic Information

  • Book Title: DNA Replication: The Regulatory Mechanisms

  • Editors: Patrick Hughes, Ellen Fanning, Masamichi Kohiyama

  • DOI: https://doi.org/10.1007/978-3-642-76988-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1992

  • Softcover ISBN: 978-3-642-76990-0Published: 27 December 2011

  • eBook ISBN: 978-3-642-76988-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XX, 422

  • Topics: Cell Biology, Biochemistry, general

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