Unicellular 3
A downloadable game for Windows
Unicellular 4 is out! Play it here!
Unicellular 3 is a roguelite cell survivor game where you play as a single celled organism that must eat and evolve to survive. Navigate the cellular world, avoiding larger predators and seeking out smaller prey!
🦠Roguelite Progression: Each playthrough has randomly generated levels, enemies, and upgrade options to ensure endless replayability.
🦠Multiple Character Classes: Choose from 6 distinct playable characters, each with their own abilities and playstyles.
🦠Deep Upgrade System: Evolve your cell with up to 12 upgrades, with 3 tiers of progression for each. Strategically choose your upgrades to complement your playstyle and find exciting synergies.
🦠Genetically Random Enemies: Encounter tons of new cell species, as well as their higher powered “mutated” forms. Each enemy’s stats (e.g.,size, speed, torque) are randomized, so each enemy cell is unique.
🦠Random Events: Some levels have random modifiers on them called events! These can make the level easier, harder, or weirder, and keep the gameplay loop fresh.
🦠Harness The Power of Chemistry: Chem molecules are single use powerups that can buff your cell, adding extra utility and depth on top of your other abilities.
🦠Simple Controls: The three button mouse-only controls are easy to pick up but hard to master. For players without a mousewheel to click, the spacebar can also be used.
Download
Click download now to get access to the following files:
Development log
- v1.2 - The Parasitic UpdateSep 11, 2025
- Patch 1.1.1Sep 06, 2025
- v1.1 - The Microchemical Warfare Update!Sep 06, 2025
- Unicellular 3 is Now Available to Play!Dec 27, 2024








Comments
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Very solid game, quite simple but addictive.
Un juego muy adictivo
Been playtesting the new update and the mosquito build is too fun
Been playtesting the new update, and it has been insanely fun! The new chems add so much fun with the added level variants.
Unicellular's newest work! Wow!
The game has evolved in a very fun way, the upgrades are interesting, the thrill of escaping from strong enemies, and the DNA collection elements are super advanced and very enjoyable!
Of course I will continue to play and aim to clear the game with all characters, meow~!
Really nice game. Had a lot of fun with it and played longer than I thought I would
Love the game!!! Its so awesome and I love the special levels