diff --git a/scripts/verify-tff-mapping b/scripts/verify-tff-mapping
index 4bdb9a4f690cb87d62defe573b8d4ae015ac661c..e053339c02ad7294c4a7335208f282936d2ae88f 100755
--- a/scripts/verify-tff-mapping
+++ b/scripts/verify-tff-mapping
@@ -364,6 +364,17 @@ tests = [
       ee/spec/graphql/types/remote_development/workspace_type_spec.rb
       ee/spec/requests/api/graphql/remote_development/workspace/with_id_arg_spec.rb
     ]
+  },
+  {
+    explanation: 'Run database dictionary related specs on db/docs changes.',
+    changed_file: 'db/docs/design_management_repositories.yml',
+    expected: %w[
+      ee/spec/lib/gitlab/database/desired_sharding_key_spec.rb
+      spec/db/docs_spec.rb
+      spec/lib/gitlab/database/dictionary_spec.rb
+      spec/lib/gitlab/database/no_new_tables_with_gitlab_main_schema_spec.rb
+      spec/lib/gitlab/database/sharding_key_spec.rb
+    ]
   }
 ]
 
diff --git a/tests.yml b/tests.yml
index 355bddb0423a7c8037c2770a5232caa9cdf7a363..9b5197d876683334f7b3fba093728524fbe13c12 100644
--- a/tests.yml
+++ b/tests.yml
@@ -146,6 +146,17 @@ mapping:
       - 'spec/db/docs_spec.rb'
       - 'ee/spec/lib/ee/gitlab/database/docs/docs_spec.rb'
 
+  # Run database dictionary related specs on db/docs changes.
+  # https://gitlab.com/gitlab-org/quality/engineering-productivity/master-broken-incidents/-/issues/6276
+  - source: 'db/docs/.+\.yml'
+    test:
+      # Found via `git grep Database::Dictionary -l spec ee/spec`
+      - 'ee/spec/lib/gitlab/database/desired_sharding_key_spec.rb'
+      - 'spec/db/docs_spec.rb'
+      - 'spec/lib/gitlab/database/dictionary_spec.rb'
+      - 'spec/lib/gitlab/database/no_new_tables_with_gitlab_main_schema_spec.rb'
+      - 'spec/lib/gitlab/database/sharding_key_spec.rb'
+
   # See https://gitlab.com/gitlab-org/quality/engineering-productivity/master-broken-incidents/-/issues/1360
   - source: 'vendor/project_templates/.*'
     test: 'spec/lib/gitlab/project_template_spec.rb'