PySCeS is the Python Simulator of Cellular Systems
AlgoSim : création, analyse et exécution des algorithmes
Allows you to build your own circuits and test them
Use simulation to perform statistical analyses.
Finite Element Rapid Analysis Lab
Queueing Theory Algorithms
mesoFON is an individual-based mangrove forest model, a KiWi extension
An open source toolkit for real space missions
The open source Algorithmic Trading System
Numerical simulation software similar to MatLab-Simulink
BlueSky Open Air Traffic sim, (Windows/Linux/Mac, Python 2.x based)