How To Make Roasted Pork Tenderloin. If you're in the mood for a simple dinner of meat and vegetables, but need to shake up your chicken breast (or pork chop) routine, pork tenderloin is your ticket. Here's our best method for making tender, juicy pork tenderloin that tastes so good it may just earn a spot in your weekly meal rotation. You'll need pork tenderloin, spices or seasonings, ground black pepper and vegetable oil.