in·ter·state
ˌin-tər-ˈstāt 
: of, connecting, or existing between two or more states especially of the U.S.
interstate commerce
in·ter·state
ˈin-tər-ˌstāt
: any of a system of expressways connecting most major U.S. cities
called also interstate highway
Examples of interstate in a Sentence
Noun
You'll get there quicker if you take the interstate.
Recent Examples on the Web
City News Service, Daily News, 8 Jan. 2026
In the mid-aughts, Hatch said, firearms were quickly dismissed as a removal method at the Bonneville Dam because using them would have meant shutting down the interstate highway that runs past the dam, as well as clearing people out of the site, which is open to the public.
—Katherine J. Wu, The Atlantic, 7 Jan. 2026
Rebecca Santana, Chicago Tribune, 10 Jan. 2026
Wenzel, who was traveling west, came to a stop on the northbound side of the interstate, when two cars were unable to avoid him and crashed into his car.
—Paloma Chavez, PEOPLE, 9 Jan. 2026
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Adjective
Abigail Luckey, 50, of North Hollywood entered a plea to two counts of interference with commerce by robbery under the Hobbs Act, which criminalizes robbery or extortion affecting interstate commerce.
—Noun
The agents eventually drove onto the interstate without detaining the driver.
—Cite this Entry
“Interstate.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/interstate. Accessed 13 Jan. 2026.
Kids Definition
interstate
1 of 2 adjective
in·ter·state
ˌint-ər-ˈstāt
: of, connecting, or existing between states especially of the U.S.
interstate highways
interstate
2 of 2 noun
in·ter·state
ˈint-ər-ˌstāt
: an interstate highway
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