When we first invested in NextGen Jane, Inc., the idea of menstrual blood as a serious diagnostic tool was still considered fringe. Today, it's being covered by BBC Future. NextGen Jane's cofounder and CEO Ridhi Tariyal makes the case compellingly in this piece: while period blood has been discarded as waste, it is an entirely under-explored milieu which can unlock answers to major medical problems- it is a natural, un-invasive biopsy with much more specificity than whole blood. The team has now analyzed more than 2,000 menstrual samples from over 330 women, and their mRNA sequencing work is identifying biomarkers that could diagnose endometriosis - a condition affecting 190 million people worldwide that takes, on average, 5-12 years to diagnose. This is exactly the kind of problem Material Impact was built to back: deep, hard science applied to a massive unmet need that the market has historically ignored. Women's health has been chronically underfunded: globally, it received just 5% of R&D funding in 2020. We're proud to have been among the earliest believers. Read the full BBC Future piece here: https://lnkd.in/emBVMmqU
Material Impact
Venture Capital and Private Equity Principals
Boston, Massachusetts 4,136 followers
Building deep tech companies powered by material science innovation.
About us
Material Impact is a champion of the bravest ideas for the future, building companies from the ground up that turn material science and deep tech innovation into products that solve enduring, large-scale, real-world problems.
- Website
-
http://www.materialimpact.com
External link for Material Impact
- Industry
- Venture Capital and Private Equity Principals
- Company size
- 2-10 employees
- Headquarters
- Boston, Massachusetts
- Type
- Partnership
- Founded
- 2015
- Specialties
- Entrepreneurial, Start-up, Venture, Healthcare, and Energy
Locations
-
Primary
Get directions
131 Dartmouth St
Floor 3
Boston, Massachusetts 02116, US
Employees at Material Impact
Updates
-
Big congratulations to our portfolio company, Foundation Alloy! The company is launching Molyclast™ MC1200 — the strongest commercially available molybdenum alloy ever brought to market. The combination of strength and manufacturability will enable new engineering capabilities for a range of customers, including those in semiconductor manufacturing, aerospace and defence, and medical imaging.
Today, Foundation Alloy is launching Molyclast™ MC1200, the latest in a new class of metals that is unrestrained by legacy metallurgy’s performance ceilings, property tradeoffs, and economic barriers to entry. MC1200 is the first metal to ever combine the best features of refractory alloys with the strength, simple manufacturing and usability of steels: ✅3x the strength of its direct competitor, recrystallized TZM, making it the the strongest molybdenum alloy on the market ✅100% elimination of embrittlement and precipitous property loss from thermal cycling ✅Room temperature ductility to enable simple manufacturing and handling without risk of breakages ✅60% or more reduction in scrap and processing time through near-net shape manufacturing, while unlocking complex geometries not possible with today’s refractory alloys At Foundation Alloy, we judge success by the value we drive for customers, not just how many metals we can simulate or test in the lab. This requires putting parts into the field, and that’s exactly what we’re doing with MC1200. As of today, MC1200 is being manufactured into parts for in-field testing at multiple customer sites and in multiple industries. It is no longer a proof-of-concept, and is moving toward full production in 2026. 👉 If you’re building hardware for extreme environments, reach out to sales@foundationalloy.com to understand how better materials can unlock capabilities now, not in some distant future. View the data sheet here: https://lnkd.in/eWm8bxAm
-
-
Material Impact is taking the stage at CES 2026! Our partners are joining leading innovators in Las Vegas to talk about how frontier technologies are shaping a smarter, cleaner, and healthier future. Corinna X. Chen will be a panelist on The Future of Cleantech. Ben Schlatka will be a panelist on Investing in the Energy Transition and will moderate Computing’s Next Frontier in Health. If you’re attending CES this year, we hope you’ll join us for these conversations. #CES2026 https://www.ces.tech/
-
Material Impact portfolio company 6K has been awarded a $1.9M research and development grant from the U.S. Defense Logistics Agency through the Battery Network Program. This award supports 6K’s work advancing domestic cathode active material (CAM) production. By leveraging 6K’s UniMelt platform, the team is enabling high-performance materials while reducing reliance on foreign sources and improving sustainability at scale. Read more below or in the press release: https://lnkd.in/eCmFPR8w
6K Energy is proud to receive a $1.9M Defense Logistics Agency BATTNET grant further developing our NMC portfolio. As the NDAA prioritizes advanced batteries and cells free from foreign entities of concern, we’re committed to supporting our warfighters with domestically produced solutions. Our UniMelt® microwave plasma process will enable the expansion of U.S. made single-crystal (SC) NMC721 cathode powder advancing secure, high-performance battery supply chains. https://lnkd.in/eEas4eng
-
We're excited to welcome Ripple Foods to the Material Impact portfolio!
Big news from Ripple Foods! We’ve just closed a $17 million strategic financing round, and we’re ready to take our next big leap forward. Why this matters: • Our mission stays the same: make high-protein, allergen-friendly plant-based milks that families can feel good about. One serving delivers up to 20g of protein, 50% more calcium than dairy, and none of the major allergens like peanuts, soy, lactose, or nuts. • This investment gives us the fuel to keep moving: launching our first organic line in early 2026, growing our retail footprint, expanding into food-service channels, and bringing more families clean-label nutrition they can trust. • We couldn’t be more excited to welcome Becky O'Grady as our new CEO. With 30+ years of experience scaling iconic consumer brands (hello, Häagen-Dazs and Yoplait), Becky knows how to grow great brands, and she knows us. She’s been on the board for five years, and now she’s leading the charge. A huge thank you to our new partners at Material Impact and Rich Products Corporation, and to our longtime supporters S2G Investments, Prelude Ventures, Fall Line Capital, EUCLIDEAN CAPITAL, LLC, Tao Capital Partners, and Tim Koogle. We’re grateful for the belief they’ve shown in our mission. Here’s what we’re excited about next: ✅ Launching our organic line ✅ Doubling down on product innovation and brand reach ✅ Growing in retailers like Target, Whole Foods, Walmart, plus new food-service channels ✅ Keeping our promise of better-for-you plant-based nutrition that works for real families Thank you to our team, our community, and everyone who’s helped us get here. Exciting things ahead! Read the full announcement here: https://lnkd.in/e5PxMKx6
-
-
Material Impact reposted this
Deep Tech for Africa: From Lab to Market In Gaborone, we marked a major milestone in our multi-year collaboration with the Government of Botswana: the in-person of Deep Tech for Africa Program, a first of its kind program accelerating Africa’s shift from consumer to creator — and ultimately exporter — of innovation. 20 scientists, engineers, and deep tech innovators from nine countries convened to tackle commercialization challenges in sectors vital to Africa’s future: agriculture, health, water, energy, mobility, industrial materials, and mining. The goal was clear: move science from the lab to the marketplace. With hands-on mentorship from Material Impact’s team and guidance from Massachusetts Institute of Technology faculty and global experts, participants worked through the fundamentals of deep tech venture creation — from de-risking science to shaping investment-ready narratives. This was active venture-building, not theory. The cohort also engaged with Botswana’s innovation ecosystem and national leaders, including Vice President Hon. Ndaba Gaolathe, underscoring the country’s vision to become a regional hub for knowledge and technology creation. This is just the beginning. Growth markets aren’t only joining global innovation — they’re shaping it. #MITKSC #TheNewCalculus #DeepTech #Innovation #Entrepreneurship #Africa
-
-
We’re thrilled to welcome Ripple Foods to the Material Impact portfolio as part of their newly announced $17M strategic financing round! Ripple is the leader in high-protein, allergen-free plant-based milks, delivering up to 20g of protein per serving, 50% more calcium than dairy milk, and none of the common allergens that make nutrition challenging for so many families. We’re proud to invest alongside Rich Products Ventures, S2G Investments, Prelude Ventures, Fall Line Capital, EUCLIDEAN CAPITAL, LLC, Tao Capital Partners, and Tim Koogle. That next chapter begins with Becky O'Grady, longtime board member and newly appointed CEO. Becky brings decades of experience scaling iconic consumer brands, from Häagen-Dazs Shops to Yoplait and is already steering Ripple toward expanded retail presence, new product lines (including organic milks launching in early 2026), and growth across both retail and foodservice channels. As Melissa Fensterstock shared: “Ripple provides a wonderful solution for millions of families seeking a nutritious, tasty, and clean alternative to dairy. With Becky at the helm and a sharp focus on growth and profitability, the company is poised to deliver strong results.” We look forward to partnering with Becky and the entire Ripple Foods team. Read the full announcement here: https://lnkd.in/e5PxMKx6
-
-
Material Impact portfolio company Amperesand CEO, Brian D., discusses how solid state transformers can impact the supply chain for data centers and other applications on CNBC. Watch the full interview here: https://lnkd.in/eKCWAchp
-
Material Impact portfolio company Amperesand has raised an $80M Series A to redefine power infrastructure for the AI era. From day one, Material Impact has been a proud partner and early investor in Amperesand—and today, we’re excited to celebrate this major milestone in their journey. Co-led by Walden Catalyst Ventures and Temasek, this round unites a strong syndicate of investors, with new participation from Industry Ventures, Acclimate Ventures, and SG Growth Capital, alongside continued support from Material Impact, Xora Innovation, TDK Ventures, and Foothill Ventures. It marks a pivotal moment as Amperesand scales its technology and expands its U.S. and Singapore footprint to meet soaring global demand for AI-ready power solutions. As lead investor from Material Impact Christian Theriault said, "Amperesand is building the world’s most efficient and versatile SST to transform how electrons are controlled, delivered, and stabilized for the world of the future." Congratulations to Brian D and the entire Amperesand team on this tremendous achievement. The future of the grid is being built right now, and we’re honored to be part of it. Press release can be found here: https://lnkd.in/gpMJpxJS #energytransition #deeptech #AIinfrastructure #gridmodernization #cleantech
Today, Material Impact's portfolio company Amperesand announced an $80M funding round, one of the largest early-stage financings of 2025 in the industrial energy sector. At its core, Amperesand builds Solid State Transformers. In practice, it is enabling the electrical grid of the future through stability, resiliency, and efficiency - capable of meeting the rapidly changing demands of the AI and electrification age. Back in 2023, we chose to partner with Xora Innovation to spin the company out of Nanyang Technological University Singapore based on five key macro tenants creating powerful tail winds: 1) The grid has lacked true transformatory innovation in decades 2) Diversifying energy sources increases the volatility of supply 3) Aging infrastructure is ill-equipped to deal with today’s peak load demand 4) Growth in AI / Data Centers + EV charging (personal, fleet, industrial etc.) will continue to drive exponential levels of electricity consumption, necessitating even more electrical transmission 5) Efficiency of energy transmission and rapid response to demand / supply imbalances will be key to securing grid stability Two years later, the above rings even truer than when we co-led Amperesand seed round with Xora Innovation (Phil Inagaki, Dickson Thian), alongside TDK Ventures (🌱🤝🌍 Nicolas Sauvage, Sam Hill) and Foothill Ventures (Eric Rosenblum) to create a powerhouse syndicate of early-stage company builders. Today we are thrilled to welcome an exceptional set of new investors to the Amperesand family: Walden Catalyst Ventures (Young Sohn, Francis Ho), Temasek (Russell Tham), Industry Ventures (Jonathan Roosevelt), Acclimate Ventures (Mark Younger, Bill Younger), SG Growth Capital (Danny Chiam). A special thank you to Phil Inagaki for the spark that helped ignite the journey, to the company CEO Brian Dow and to the entire Amperesand team who has taken our early vision and transformed it into the groundbreaking reality that it is today: *Building the world’s most efficient and versatile SST to transform how electrons are controlled, delivered, and stabilized for the world of the future* #energyinfrastructure #AIpower #SST #powerelectronics #seriesA Want to shape the electrical grid of tomorrow? Please don’t hesitate to reach out to Brian Dow and his amazing team at Amperesand! • Business Inquiries: https://lnkd.in/eCXeMx-f • Careers: https://lnkd.in/e-5bvg-N https://lnkd.in/emuGhAwK
-
Material Impact reposted this
Last week reminded me why I started this journey. For years, I’ve believed deeply in building African solutions for African problems especially in the livestock sector, where farmers carry generations of hope, identity, and economic stability on their shoulders. Being selected for the MIT Kuo Sharper Center for Prosperity and Entrepreneurship Deep Tech for Africa Program, hosted in partnership with the Government of Botswana, Material Impact, and BDIH, felt like stepping into the future we’ve always imagined but rarely get spaces to build boldly. Over the past week, I stood alongside brilliant founders from across the continent people rewriting what deep tech means for Africa’s food systems, health, climate, and security. We were challenged, refined, stretched, and supported. And for Nature Sentinel, this program became a turning point: 🔹 We sharpened our customer-driven value proposition 🔹 Re-designed our business model for scale 🔹 Strengthened our roadmap toward field testing 🔹 Learned how to tell our story with clarity and courage But beyond the tools and frameworks, what stayed with me was the humanity. The encouragement. The belief. The reminder that innovation is not just about technology it’s about the lives we touch. To Adam Sharkawy, Ridhi Tariyal, Ezgi Emiroglu, Christian Theriault, Adel Boseli, Melissa Fensterstock, and the entire MIT KSC team — thank you for your generosity, your honesty, and your commitment to seeing African deep tech succeed. I leave this program more grounded in my purpose, more refined in my thinking, and more inspired to contribute meaningfully to Botswana’s agricultural future. Onwards with gratitude, conviction, and a renewed sense of responsibility. #MITKuoSharperCenter #DeepTechForAfrica #BotswanaInnovation #NatureSentinel #AgritechAfrica
-