During filming, a French tourist mistook Richard Gere - who was in full wardrobe - for a homeless man and gave him some leftover pizza. Gere happily took the bag and thanked the woman. The tourist later found out that it was Gere after reading about the film in a New York Post article.
As filming commenced, Richard Gere was worried that he would be recognized on the streets, shattering the illusion of him playing an essentially invisible man. He needn't have worried. Of all the thousands of passers-by that he encountered in the streets, only 2 asked him if he was Richard Gere.
More than 20 attendees walked out during the Toronto International Film Festival screening of the film.
Note that cinematographer Bobby Bukowski frequently shoots the character George at strange angles, through windows and in reflections. This is to indicate his disassociation with normal society.