This film was made as a proof of concept, with plans to adapt it into a feature-length film, television series, or comic book.
The name "James Wilson" came from combining the names of Marvel superheroes Wolverine (James Howlett) and Deadpool (Wade Wilson). Just like James, both of these heroes have healing abilities.
Shot in 6 and a half days, with a post-production time of only a month and a half to meet the premiere date.
In an early draft of the script, Alpha attempts to kill himself over and over after attending Sarah's funeral. Both scenes were ultimately cut. The funeral scene was too high budget, and the filmmakers found that the attempted suicide scene was too dark for the overall tone of the movie.