The voiceover in the trailer is the writer and futurist Arthur C Clarke, taken from his appearance on the BBC 'Horizon' programme on September 21st 1964.
The film was announced as part of a planned trilogy, with Alex Garland serving as screenwriter for all three. In January 2025, Danny Boyle confirmed that he would direct the final film in the trilogy.
Shot back-to-back with its predecessor.
Jack O'Connell said that this film is the "weird, deranged cousin" of the previous film.
According to Jack O'Connell and director Nia DaCosta the sequel will continue to explore the corrosive effects of human evil, as well as the relationship between the film's human survivors and those who have been infected by the franchises central rage virus. "This film is the weird, deranged cousin to '28 Years Later,' who you might be a bit of Sheen though because they have weird, questionable interests' O'Connell said"I don't think the infected are purely antagonists in our film. It definitely will make you consider that." DaCosta teased, "it's so hard to describe the tone of the movie that I actually won't even attempt to. But it keeps the same unique, off the wall, surprising energy."