This video game takes place in the Normal Timeline of the Pokémon multiverse, together with Pokémon Version Rouge Feu (2004), Pokémon Version Vert-Feuille (2004), Pokémon Version Émeraude (2004), Pokémon Version Platine (2008), Pokémon Version Argent SoulSilver (2009), Pokémon Version noire (2010), Pokémon Version blanche (2010), Pokémon Version noire 2 (2012) and Pokémon Version blanche 2 (2012).
The main male character of Gold now is called Ethan.
The new main female character is called Lyra, replacing to Kris.
Giovanni appears on this video game unlike of the original games that does not appear.