Ron Chaney (Bela Reinhardt) is the grandson of Lon Chaney Jr., who played Lawrence Talbot / The Wolf Man in Le Loup-garou (1941), Frankenstein rencontre le loup-garou (1943), La Maison de Frankenstein (1944), La maison de Dracula (1945) and Deux nigauds contre Frankenstein (1948).
Michael R. Thomas's last film; it's dedicated to his memory via end credits.
The title is clearly a nod to the, "The house of" franchise/original Frankenstein series. I.E. The house of Frankenstein, house of Dracula, and etc.