During game play the characters will occasionally reference dialogue from the Firefly (2002) series such as "the 'verse" and "gorram it!"
Nathan Fillion and Tricia Helfer dated and were briefly engaged but broke up due to filming schedules, very similarly to their characters.
Halo 3: ODST was remastered for the Xbox One as DLC for the Master Chief Collection. This version displays in 1080p at 60 frames per second, and features altered/improved lighting and touched up textures. A light rain effect has also been added to the "Mombasa Streets" levels. Rain was originally intended to be in these levels for the Xbox 360 version, but was not possible at the time due to technical limitations.
Adam Baldwin's character while holding a rocket launcher can sometimes be heard yelling; "Here's Vera!". This is a reference to Joss Whedon's Firefly, as Baldwin's character also had a large gun named "Vera".