Ultimo appears as a massive battle suit that has been fused with the consciousness of Kearson DeWitt. In the canon comic Captain America: Road to War, Ultimo is a giant robot created by HYDRA from the remains and parts of Ultron Sentries destroyed in the Battle of Sokovia and is deployed in Eastern Europe against the Avengers.
Ghost appears in the Wii and PSP versions of this game and is a professional corporate saboteur who uses a suit that allows him to become invisible, provided that he does not touch liquid. Like in the comics, Ghost is a male character, but when Ghost finally appeared in the MCU in Ant-Man et la Guêpe (2018), Ghost was instead changed to a female corporate saboteur named Ava Starr.
Firepower appears in the PlayStation Portable and Wii versions of this game and is a mercenary hired by A.I.M. with a suit of armor similar to those worn by Iron Man and War Machine. In Iron Man 3 (2013), Jack Taggart does work for A.I.M. but is not a mercenary nor does he have armor or the alias Firepower, but is instead a former United States Armed Forces soldier who is addicted to Extremis.
A.I.M. appear as a secret weapons and intelligence agency who is frequently in conflict with Iron Man. In Iron Man 3 (2013), A.I.M. is a scientific research and development agency funded by the government, and Tony Stark has had no previous encounters with them since meeting Aldrich Killian in Bern, Switzerland on New Year's Eve 1999.