The production was set to shoot on one of Toronto's largest studios but the day before they were due to begin filming, it burned down.
Claire Redfield wears a red vest, her primary outfit from her game appearances.
The original plan was to have some brief flashback sequences which would elaborate on the backstory of Chris and Claire Redfield, and reveal the ongoing search of the two siblings to find one another. This is a storyline well established in the video games, where Claire Redfield comes to Raccoon City to search for Chris in Resident Evil 2 (1998), but doesn't meet up with him until Resident Evil: Code: Veronica (2000). The idea was scrapped.