In an interview shortly after the movie was released, Betsy Rue, who plays Irene, the girl who has sex with the truck driver in the motel, said it was her idea to end up running through the parking lot stark naked. It was also her first nude scene. According to her, after she was cast "they wanted to make sure that I was going to be comfortable with everything before I did it, so I knew what it entailed before I went in and actually, the end product was a lot more than they expected. When you're watching the movie, if you look at the part where I take the gun out of the purse, before I come out into the parking lot, I grab a sheet off the bed. We did this many times with the sheet, and it just wasn't working, so I said, 'Forget the sheet, I am leaving the sheet behind.' So that's how I ended up getting so much more nude. I said, 'Forget it, if you want this, I'm going to go balls to the walls and here it is.'" She added "Because, as an actor, I just felt a lot better forgetting the sheet. I felt like it was more real. I felt like I was in my reality. I was, like, 'I would not be worrying about this stupid sheet right now! I just want the tape back.'"
The first R-rated film in the USA projected in Real D technology.
A flyer on a wall indicates that Valentine's Day is Saturday, February 14th. That would mean the previous day is Friday the 13th.
There was also an episode titled "My Bloody Valentine" on Jensen Ackles' TV series "Supernatural."
The screenwriter, Todd Farmer, also appears in the film playing the role of Frank the trucker. Farmer's wife Melanie is thanked in the credits for allowing him to get naked.