In the episode Big Time Songwriters, the band writes the song "Oh Yeah". In real life, the guys wrote that song for their first album "BTR" and was the only song on that album especially written by them.
Carlos PenaVega and Logan Henderson had relationships with the Vega sisters. PenaVega is married to Alexa PenaVega and Henderson was in a relationship with Makenzie Vega until they broke up.
In the show the main characters start off as hockey players, while in real life, only three out of four of the boys had ever played hockey before the show. Kendall hadn't.
The song "No Idea" is in fact a cover of a song of same name by All Time Low.
In one episode, Patchy the Pirate from SpongeBob SquarePants made a cameo.