Despite being based on a Marvel comic book and being a production of Marvel Television, the Marvel logo does not appear anywhere in the marketing material for the series or in the series itself. This was done is such order because Marvel Television was being integrated within Marvel Studios and was no longer a subsidiary, but rather a label company.
"Ana" is short for "Satana," Daimon's sister in the comics.
This was the last TV series produced by Marvel Television before it merged into Marvel Studios, and has no involvement with the MCU.
The asylum used is the same one in 'Supernatural' and 'Arrow.'
Hulu announced in 2019 they would produce this and a Ghost Rider series. Helstrom ended after one season and the streaming service could not proceed with Ghost Rider due to creative differences.