Producer Victoria Burkheart had previously been involved with early development on Neill Blomkamp's canceled Alien 5 film.
The Xenomorph was originally intended to be portrayed with a mix of practical effects and CGI. When it became apparent during development that this would be too expensive and some of their shots couldn't be done practically, they settled for an all-digital creature instead.
When creating the six anniversary shorts, participants were told that their films should take inspiration from only the first Alien film. Despite this, the alien model used in Alien: Ore features the ridged head design seen on the creatures used in the first sequel, Aliens. This was an unintentional mistake, as the 3D model used predated the short, and it would have been too expensive to commission a new model.