A total of 80 automobiles were destroyed during filming.
To make it look like Robert De Niro and Natascha McElhone were actually driving during the car chase, right-hand-drive cars were used, with the passenger side made to mirror the real controls. The cast members then mimicked the stunt drivers' movements.
Skipp Sudduth requested to do his own stunt driving during the car chases, and John Frankenheimer agreed. Frankenheimer told Sudduth, "I don't wanna see any brake lights."
The talk about the "man in the wheelchair" is referencing the book "The Bourne Identity" (1980) by Robert Ludlum. The Man in the Wheelchair was M. Chernak, a mercenary broker who Jason Bourne killed.