Trivia

All external space scenes and many sets are lifted from one of Don Keith Opper's earlier films, Androïde (1982).

First Critters movie where Don Keith Opper is the highest billed actor.

Filmed simultaneously with Critters 3 (1991), from February 1991 until July 1991.

Critters 4 is the only Critters movie where the Critters are unable to shoot poison darts at their victims.

Terrence Mann and Don Keith Opper have appeared in all four films in the series.