The original play opened on Broadway in New York City at the Playhouse Theater on 30 January 1935 and closed on 9 January 1937 after 835 performances. Teddy Hart and Sam Levene originated their movie roles in the play, and the cast also included Shirley Booth as Mabel, and Millard Mitchell as Charlie. The popular play had Broadway revivals in 1942, 1970 and 1993.
The Milton Bradley Company released a board game in 1936 called "3 Men on a Horse." The graphics on the box declare it "a sparkling game of chance for everybody" and "from Warner Bros.' laff hit!"
The film was given a "B" rating by the National Legion of Decency - morally objectionable in part for all.
"The Screen Guild Theater" broadcast a 30-minute radio adaptation of the movie on February 28, 1943 with Sam Levene reprising his film role.
"Theater Guild on the Air" broadcast a 60-minute radio adaptation of the movie on January 1, 1946, with Sam Levene reprising his film role.