Bob the Drag Queen, winner of Rupaul's Drag Race season 8 and friend of Trixie and Katya's, was brought in to guest co-host with Trixie for the last five episodes. Katya later stated that the reason was because she fell back into methamphetamine addiction and had a mental breakdown, going back to live with her family and later going to rehab to recover. She has talked before about drug and alcohol addiction prior to the show, and later tweeted a thank you to Bob for filling in for her. When the show returned to the original UNHhhh YouTube series, Katya returned to co-hosting.
The series is a spin-off from Trixie and Katya's YouTube series "UNHhhh", which became a huge hit, and was itself a spin-off from the pair's guest appearance on another YouTube series, Fashion Photo Review.