Writer, producer and director Luc Besson was accused of sexual misconduct during production of this movie. Although no charges were filed due to lack of evidence, the studio and distributors subsequently distanced themselves from the movie, releasing it without official screenings and with only a minimum of publicity. This movie, which was supposed to be the breakthrough for model-turned-actress Sasha Luss, only made thirty million dollars worldwide, which could mean the end for Besson's EuropaCorp studio, which was already struggling from his previous box-office failure, Valérian et la Cité des mille planètes (2017).
Sasha Luss says that almost every conversation she had with Cillian Murphy was about his wife (Yvonne McGuinness), or about his wife with a dog, or about his dog.
The K.G.B. building where a car is waiting for Anna (Sasha Luss) during the climactic fight is the Chemical Department of Moscow State University. The main building (tower) of the university is briefly visible.
Helen Mirren plays a Russian which is not surprising, as she is half-Russian. She was born Helen (or Yelena) Mironoff, and her father was an emigrant to England from Smolensk, Russia.
The scene where Anna leans exhaustedly against a wall in the shower following a hit job gone wrong is a tribute to that of Jean Reno's character in almost identical circumstances in Besson's Léon (1994)