Jason Statham has expressed his love for The Expendables. On co-star Sylvester Stallone, he said "Working with Sylvester Stallone is beyond a pinch yourself moment. I remember growing up watching his films, and to be directed by him, and to be in a movie that he's produced, and to be shoulder to shoulder with Sly is a privilege any man who loves action movies would never turn their nose up at. I mean, it's terrific. I'll do as many as he wants."
While promoting the DVD/Blu-ray release of Os Mercenários 3 (2014), Sylvester Stallone already commented that if a fourth film were to happen, it would definitely be R-rated, unlike the PG-13 rated The Expendables 3. As he stated on the matter: "Absolutely unequivocally yes. I believe it was a horrible miscalculation on everyone's part in trying to reach a wider audience, but in doing such, diminish the violence that the audience expects. I'm quite certain it won't happen again."
Filming for this movie wrapped on October 15, 2021, this will be the first Expendables film to have any scenes shot in the United Kingdom. Sylvester Stallone has said that he's "taking a backseat" for this movie as Jason Statham's character Lee Christmas will be the central character in this movie.