Io was the original title of Outland: Comando Titânio (1981) but at that time testing showed people read the name Io as 10, and so the name was changed.
Micah recites an excerpt from The Symposium about how people search for their other halves and attributes it to Plato. The essay was actually written by Aristophanes.
This movie features a quote from The Iliad, by Homer, who also wrote The Odyssey. 2001: A Space Odyssey also involves a mission to Io.
While there are very few characters in this movie, two have been in Marvel movies: Danny Huston portrayed Colonel William Stryker in X-Men Origens: Wolverine (2009) and Anthony Mackie plays Sam Wilson (aka: Falcon) in the Avengers franchise.