In the song Hauli Hauli, when Fardeen Khan makes the entry with Akshay Kumar, the title Heyy Baby is sung as part of the song, marking their reunion since their movie Heyy Baby in 2007.
Akshay and Taapsee have never been paired whenever they worked since Baby, Naam Shabana, Mission Mangal and now in Khel Khel Mein.
Akshay Kumar's scenes with Chitraganda Singh have a reference to Desiboyz.
The film is a remake of An Italian film Perfect Strangers 2016 which has been remade in 50 languages.
Fardeen Khan's comeback to the silver screen after 14 years. Fardeen Khan hold's the record of the only hero in Hindi films to have the longest gap of 14 years between his movie releases. Kamal Haasan's last original Hindi release was Dekha Pyar Tumhara in 1985, and he returned to Hindi films with Chachi 420 in 1997. In between, he had several movies dubbed and released in Hindi. Rajnikanth's last original Hindi release was Bulundi in 2000. He had a special appearance in that film. After that he had several of his films also dubbed in Hindi. Fardeen's father Feroz Khan faced the camera after 11 years gap with Janasheen. The role was of the film's villain. The only other lead actor to return to acting of 12 years was Randhir Kapoor with the film Mother in 1999. Randhir's previous release was the long delayed film Khazana in 1987. The only difference was that Randhir Kapoor came back in a elderly character type role in the film (Though he was promoted in the film's publicity). So that makes Fardeen Khan the only lead actor in Hindi films to have the longest gap between his last and next release. His last release in 2010, Dulha Mil Gaya, saw him in the lead role. In 2024 he returned as one of the lead male role's with Khel Khel Mein and not a character role.