Stan Lee makes a cameo in season one, episode five.
Lyndsy Fonseca and Noah Bean met on the show and have been in a relationship since. They married on October 2, 2016.
Sonya is the only member of the regular cast whose last name is never revealed.
Maggie Q is the second Asian-American actress to star as the main character in an American drama series. Anna May Wong starred in "The Gallery of Madame Liu-Tsong" in 1951.
Nikita uses the cover name "Josephine" in the season one episode "The Next Seduction." In the original series La Femme Nikita (1997), "Josephine" is the code word Nikita is always given to activate her for a mission. The original Michael would call her and only say "Josephine" and then hangs up.