The appearance of "Scooby-Doo" hero Shaggy Rogers in a Mortal Kombat feature is a homage to the "Ultra Instinct Shaggy" trend that started in 2017. It got so popular that fans were campaigning for Shaggy to appear in a Mortal Kombat game. The logo joke is the closest fans will get to an official Scooby-Doo/Mortal Kombat crossover.
Johnny Cage has his design based on his Mortal Kombat X standard costume.
Kitana's voice actress in the movie, Grey Griffin was originally going to voice the character in Mortal Kombat X but previously bowed out to the role due to her pregnancy with her second child at the time, leaving Karen Strassman reprising the role instead.
Dave B. Mitchell reprises his role as Sektor from Mortal Kombat 11.
Voice actor Matthew Yang King who voiced Liu Kang and Fujin in Mortal Kombat 11 also voices Kung Lao in this film