Pokémon Yellow was one of the few games that was able to interact with the Game Boy Printer.
The surfing Pikachu obtainable in this version using Pokémon Stadium or from Nintendo events has been referenced before on the anime - as "Puka" who was a Pikachu with blue eyes belonging to a surfer. Gaining this Pokémon also unlocks a special mini-game, "Surfing Pikachu".
Pokémon Yellow was the 4th Game Boy game to feature a yellow cartridge. The other three are Donkey Kong Land (1995), Donkey Kong Land 2 (1996) and Donkey Kong Land III (1997).
The infamous Old Man Glitch which allowed players to encounter MissingNo. in the wild was patched out in this version. That said, through other game glitching methods it's still possible to encounter MissingNo. though it's difficult as it will often crash the game.
This game features another design of Cerulean Cave, having already been redesigned between the original Poketto monsutâ midori (1996) and Japanese Pokémon: Versão vermelha (1996) which in turn carried into Japanese and International Red & Pokémon: Versão azul (1996).