When Delta Burke made her first entrance on the show, she expected to stop for a brief moment for applause and then continue the scene. Instead she was met with a standing ovation from the audience - which stretched on so long that she broke character, walked off, grabbed creator Linda Bloodworth-Thomason's hand and dragged her on stage to show that they had made amends.
Teri Garr walks with a slight limp throughout the series. She had already been diagnosed with multiple sclerosis, though this was not publicly known until 2002.
Julie Hagerty was cast as Jennifer Malone, but a scheduling conflict arose which prevented her from appearing in the first few episodes, so Valerie Mahaffey filled in. Hagerty then starred in two episodes and abruptly quit, so Mahaffey returned for one final appearance and then the character was written out.
This spin-off came 4 years after Delta Burke's bitter departure from Designing Women (1986), which was the subject of extensive tabloid fodder. Burke eventually reconciled with creator Linda Bloodworth-Thomason and agreed to reprise her role in this series, citing it as a major turning point in her life.
After the pilot was shot and the series was picked up, Patricia Heaton got pregnant. Rather than writing her pregnancy into the show, they masked it by changing her hair, wardrobe, and keeping her character confined to a bed in the series finale.