The name and title of Peter Haber's character - Dr. Max Adrian Busé, the name abbreviated M.A. Busé as seen on the door to his offices - is an obvious nod to Fritz Lang's classic O Testamento do Dr. Mabuse (1933), which this film was inspired by.
The first film in the series not to feature Gösta Ekman and lead character Charles-Ingvar 'Sickan' Jönsson also doesn't feature the classic theme music by Ragnar Grippe, instead a new theme was composed by Thomas Lindahl.