Kevin Conroy who plays Edward 'Ted' Kennedy in this series later became the voice of Batman on Batman: A Série Animada (1992). JFK's real-life press secretary, Pierre Salinger (portrayed in this series by Peter Boyden) played a villain on Batman (1966).
The mini-series takes place from November 8, 1960 to November 22, 1963.
First aired on NBC on Sunday, November 20, 1983, at the same time that ABC was broadcasting O Dia Seguinte (1983).
Of the political Kennedy brothers trio (John, Robert, Ted). The real-life Ted Kennedy was the only one still alive at the time of the miniseries premiere in 1983 (living till year 2009). Ironically, Kevin Conroy (who portrays Ted) ended up predeceasing both Martin Sheen (who plays John F.) and John Shea (who plays Robert) when he died in 2022.