1942 was a banner year for Tim Holt. He starred in seven B westerns - more than any other year in his prolific career. Pirates of the Prairie was the sixth movie of the seven, followed by Red River Robin Hood.
This is a remake of George O'Brien's western A Legião dos Renegados (1940), released just two years earlier. Many of the scenes and much of the dialog are taken directly from the previous film's script. Several of Tim Holt's westerns are remakes of previous features starring George O'Brien, such as O'Brien's No Campo Inimigo (1938), which was remade as Tim Holt's Afrontando o Perigo (1942). Tim Holt actually co-starred with George O'Brien in the 1938 film.