Kevin Conroy and Mark Hamill reprise their roles as Batman and the Joker in this game, instead of Troy Baker and Christopher Corey Smith.
The game's storyline takes influence from the New 52 storyline, "Forever Evil" which ran from 2013-2014, with the inclusion of the Crime Syndicate of America and the game's focus on villains.
Raven and Beast Boy both are voiced by the same people that originally did it in Os Jovens Titãs (2003).
Unlike the Lego Batman trilogy, this is the first Lego video game to focus entirely on villains of the DC Universe, similar to the villain levels featured in Lego Batman: The Videogame (2008).