Among the locations the player can visit are the firehouse and the apartment building from Os Caça-Fantasmas (1984), the soup restaurant from Seinfeld (1989), Jessica Jones' office, Matt Murdock's law offices, and the Insomniac Games studio.
Every time Spider-Man throws an enemy off a building, no matter by which means, they never hit the ground. Instead, they get automatically webbed against the wall. This was done to contribute to Spider-Man's "no-kill" rule.
Some of the characters in the game are modeled after their real-life actor counterparts.
Insomniac says that this game is the first in a Marvel Gaming Universe, as they have plans to make more Marvel games.