- Miss Arizona 1980 in the 1981 Miss America pageant.
- Served on the board of directors of the Montana Shakespeare Company in Helena, Montana.
- Both in Everwood: Uma Segunda Chance (2002) and Desperate Housewives (2004), she plays a family mother whose death in the pilot of the series sets the events of the show in motion. She reappears throughout the shows in flashback scenes and dream sequences.
- Played two separate characters in Tropas Estelares (1997) and Tropas Estelares 2 (2004).
- Graduated Magna Cum Laude from Arizona State University with Bachelor of Music in Musical Theatre.
- 1978: Graduated from Sandy High School in Sandy, OR.
- Brenda taught yoga in Los Angeles, California.
- Married for the 2nd time her longtime boyfriend John Farzad Strong following a 4-month-long engagement. (maio de 2015)
- Replaced Sheryl Lee who was originally cast as Mary Alice Young for the ABC series Desperate Housewives (2004) in its pilot episode.
- Also worked with Felicity Huffman on the short lived Sports Night (1998) program created by Aaron Sorkin of West Wing: Nos Bastidores do Poder (1999).
- She played Cliff Barnes' "one night stand" in the Dallas (1978) 1987 episode Cat and Mouse (1987) and played Bobby Ewing's third wife Ann in Dallas (2012) from 2012 to 2014.
- She and her future Desperate Housewives (2004) co-star Marcia Cross both starred in Everwood: Uma Segunda Chance (2002). Strong guest-starred in a few episodes while Cross was a steady cast-member from 2003-2004. They never were in the same episodes. They also both guest-starred in different episodes of Ally McBeal: Minha Vida de Solteira (1997). They separately guest starred in back-to-back episodes of Seinfeld (1989) during season nine. Cross appeared dating Jerry as life-saving dermatologist Dr. Sara Sitarides, and Strong in her recurring role as Sue Ellen "The Bra-less Wonder" Mischke.
- Played a psychiatrist in Get a Job (1998), A Casa do Terror Tract (2000) and in the CSI: Investigação Criminal (2000) episode, Overload (2001). All three times, her patient was a troubled young boy.
- Has a son named Zakery Henri (aka Zak Henri, b.1994) with her now ex-1st husband Tom Henri.
- Has been on five shows on The WB - Sétimo Céu (1996), Gilmore Girls: Tal Mãe, Tal Filha (2000), Dawson's Creek (1998), and Everwood: Uma Segunda Chance (2002), The Help (2004).
- Was among the guests at Marcia Cross' wedding to Tom Mahoney.
- Her uncle was painter Ray Strong.
- Brenda appeared in an episode of Jornada nas Estrelas: A Nova Geração (1987). She also starred in Tropas Estelares (1997) (When the Bough Breaks (1988)(#1.16) to be exact) which used the term "warp drive" for the technology to travel faster than light.
- She and future Desperate Housewives (2004) co-star Felicity Huffman both starred in Sports Night (1998). Strong guest-starred in several episodes while Huffman was a regular cast-member for both seasons. In the series, Strong was sleeping with both Huffman's fiancé (Ted McGinley) and Huffman's co-worker (Peter Krause).
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