O jovem Angus "Mac" MacGyver trabalha para uma organização clandestina dentro do governo dos EUA, sempre confiando em suas habilidades não convencionais de resolução de problemas para salvar vidas.
Ex-MI6 agent Russ Taylor recruits former Phoenix Foundation members Mac, Riley, Bozer, Matty and Desi to hunt down a bio-weapon that's planned to be used by a mysterious organization for a devastating attack on a major U.S. city.
A general gives Phoenix a chance to regain its security clearance by testing a military lab's security, stealing a chip there. Things don't go as planned.
Harry Langford helps Five-0 investigate a series of murders that follow the plot of a fabled unpublished crime novel from the 1920s. Also, Tani and Junior's friendship takes a meaningful new turn.
During COVID-19's first stay-at-home order, as Mac, Bozer and Riley quarantine together, they try to stop a crime in progress at their neighbor's house.
The governor of Hawaii authorizes Navy intelligence officer Steve McGarrett to put together a special unit whose first job is to capture the man who killed McGarrett's father.
McGarrett is on the trail of an escaped prisoner who is trying to take advantage of an opportunity to get his money back from his former crime partner.
One daughter of the U.S. ambassador to the Philippines is killed and another daughter is missing, and governor Jameson brings McGarrett's team to lead the investigation.
McGarrett places himself in the middle of a hostage situation on the USS Missouri. The hostage-taker is an ex-Navy SEAL suffering from post-traumatic stress disorder, who is the prime suspect in the murder of his wife.
When an escalating gang war spills into the stands of the local high school football game, injuring several bystanders and killing a gang leader, Five-0 uncovers an unlikely partnership between Samoan gangs and a mainland mob.
Five-0 is assigned to help stop an assassination plot against a despicable foreign leader, with the help of one of McGarrett's old SEAL buddies. But is his friend actually in on the conspiracy?
When the CEO of a hugely successful surf company is murdered, Kono revisits her past while Five-0 is thrown headlong into the varied but interconnected worlds of North Shore surfing.
The team is on the trail of a team of bandits who are planning a robbery during the Honolulu triathlon, and they are forced to turn to Danno's ex-wife for help.
After a woman escapes from abduction and her new husband is found dead in their hotel room, Five-0 discovers that they are dealing with a serial killer who targets newlywed couples.
McGarrett's father's toolbox is stolen, and his sister is kidnapped for investigating their mother's death. McGarrett soon discovers that his father was investigating a suspected Yakuza leader before his death.
McGarrett brings his mother back to the island. But her life may be in danger after Wo Fat escapes from prison with the help of an unlikely partner: Frank Delano.
