East West 101 is set around the Major Crime Squad in metropolitan Sydney. It is based upon the experiences of actual detectives in a crime unit in Sydney's western suburbs.
The detectives of the Kingsway Major Crime Squad fight to preserve their Pacific paradise, while dealing with the personal and professional tensions affecting their work and lives.
A new detective is attached to a major crime squad in a tough southern district of Sydney. This creates tensions within the squad, particularly when the squad is called out to a homicide and the prime suspect appears to be the new appointment.
A suspicious death on an Army base brings out Harriet and Joe to investigate. The death would appear to be a suicide but Joe is not sure, suspecting the military of closing ranks to protect one of their own.
An elderly man is found dead in his home. His body is bound to a chair, his home has been ransacked, and a mysterious hole has been dug in his backyard.
The investigation surrounding the violent stabbing death of a pizza delivery boy takes an unexpected turn when the suspect brought in for questioning is found to be Ted Hudson's son Daniel, a paranoid schizophrenic.
While testifying in the trial of high-profile criminal Nick Hammer, Sophie is humiliated on the witness stand by an aggressive defence lawyer who calls her credibility into question.
The discovery of a blood-soaked four-year-old girl walking alone on the roadside leads detectives Hill and Walker to the scene of a bloody massacre that has left an entire family dead.
The pursuit of a stolen car ends tragically when a police officer is killed after an iron bar is thrown from an overpass, smashing through the car's windscreen and piercing the driver's chest.
The Kingsway detectives are called in when an eleven-year-old girl is abducted from outside her school and held for ransom. The family's recent lottery win would appear to explain why their daughter was targeted.
A series of poisonings are linked to a local supermarket chain. Products at the store are being tampered with and demands have been made by an extortionist.
The stabbing death of an Olympic rower appears to be an open-and-shut case after a suspect's quick confession but as the guilty man's girlfriend accused the rower of rape suggests the murder may have been a revenge killing.
The Kingsway detectives investigate the brutal murder of a Filipino woman. They suspect the involvement of the woman's husband and possibly one or both of his parents but all parties have alibis and no one is prepared to talk.
Over the years, Detective Sergeant Joe Hill has had the highly dubious Nick Karados in his sights many times. But Nick has always managed to stay just out of Joe's reach. Could that be about to change?
The death of a fruiterer seems the result of a war between two organised crime gangs. Or is it just personal? Could Harriet be suffering from a case of the green-eyed monster?
A complaint filed against Hudson by an ex-con who accuses him of fabricating evidence places his career on the line when he loses the Commissioner's confidence.
A security guard is murdered during a break and enter at the fortress-like home of a wealthy banker. The only forensic evidence is a child's tooth discovered near his body, but could a child be capable of such a horrific crime?
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