- In 1988 Marlon Brando (impressed by L'oeil du tueur (1987), which Guest cast and played the part of Caryanne in) called director Donald Cammell and invited him to write and direct "Jericho", an ultra-violent action thriller. Brando would play Billy Harrington, a former CIA assassin blackmailed by the CIA into carrying out one last mission. Guest put together a cast including the then-unknown Julia Roberts as Brando's daughter, Benjamin Bratt as her love interest, Robert Duvall and Morgan Freeman as CIA operatives. Producer Elliott Kastner paid Brando $3 million up front, but after eighteen months of work, while on preproduction in Mexico and with shooting only days away, Brando dropped out, claiming he couldn't get insurance. Kastner went bankrupt, and Cammell and Guest eventually went on to work on Wild Side (1995) together.
- Sister-in-law of Christopher Guest, Jamie Lee Curtis.
- Mother of actress Elizabeth Guest and producer-executive Will Rack.
- Aunt of Annie Guest and Ruby Guest.
- Stepmother of Julia Guest.
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