Trivia

In Living Color (1990) alum Jim Carrey credits Keenen for giving him his start in comedic acting.

Was in a long-term relationship with Brittany Daniel, from the television shows, The Game (2006) and Sweet Valley High (1994), and the Wayans' films, Little Man (2006) and FBI - Fausses blondes infiltrées (2004).

Has five children by ex-wife Daphne Wayans (nee Daphne Polk): Jolie (b. June 25, 1992) Nala (b. March 4, 1996) Keenen Jr. (b. September 14, 1998) Bella (b, March 4, 2001) and Daphne Ivory (b. July 12, 2003).

Parents are Howell and Elvira Wayans. Brother of Dwayne Wayans, Damon Wayans, Kim Wayans, Nadia Wayans, Marlon Wayans and Shawn Wayans. Also has sisters Elvira Wayans, Diedra Wayans, and Vonnie.

Keenan attended college at Tuskegee Institute in Alabama but dropped out his senior year to pursue comedy full time. His comic influence is Richard Pryor.

Is a member of Alpha Phi Alpha Fraternity Inc.

Keenen Ivory Wayans was the first movie director that Hollywood ever allowed to depict a rape scene that was designed specifically for laughs. (Little Man (2006)).

Father of Jolie Ivory Imani Wayans, Keenen Ivory Wayans Jr., Nala Wayans, and Bella Wayans. Uncle of Craig Wayans, Damon Wayans Jr., Michael Wayans, Cara Mia Wayans, Kyla Wayans, Damien Dante Wayans and Gregg Wayans.