13 wins & 45 nominations
- 2017 Nominee Daytime Emmy
- Outstanding Game Show
Shared with: David Arquette · Craig Ferguson · Richard Gerrits · Jennifer Mullin · John Quinn · Laura Robinson · Scott St. John · Thea Mann · Jennifer Langheld
- 2021 Nominee Primetime Emmy
- Outstanding Variety Special (Pre-Recorded)
Shared with: Ben Winston · Kevin Bright · Marta Kauffman · David Crane · Jennifer Aniston · Lisa Kudrow · Matt LeBlanc · Matthew Perry · David Schwimmer · Emma Conway · James Longman · Stacey Thomas · Brett Blakeney · Dave Piendak · Carly Segal · Guy Harding · Paul Monaghan · James Corden · Tracie Fiss · Mike Darnell · Brooke Karzen
- 1995 Winner Golden Apple
- Female Discovery of the Year
- 2010 Nominee Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 2015 Nominee People's Choice Award
- Favorite Cable TV Actress
- 2014 Nominee People's Choice Award
- Favorite Cable TV Actress
- 2012 Nominee People's Choice Award
- Favorite TV Comedy Actress
- 2011 Nominee People's Choice Award
- Favorite TV Comedy Actress
- 2002 Nominee Razzie Award
- Worst Screen Couple
Kurt Russell and EITHER Kevin Costner or Courtney Cox.Shared with: Kurt Russell · Kevin Costner
- 2000 Winner TV Guide Award
- Editor's Choice
Shared with: Jennifer Aniston · Lisa Kudrow · Matt LeBlanc · Matthew Perry · David Schwimmer · Jane Sibbett · John Christopher Allen
- 2023 Winner OFTA TV Hall of Fame
- Actors and Actresses
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