- In La Vie des autres (2006), he plays an agent of the Staatssicherheit, East Germany's main security and intelligence organization. The role had particular resonance for him, as he was under surveillance by the Stasi, being a noted theater actor. In a tie-in book promoting the film, he claimed that his ex-wife Jenny Gröllmann was registered as an informant during their marriage. Nevertheless, she denied those allegations until her death.
- He and other activists initiated the demonstrations against the East German communist regime in Berlin (November 1989).
- Tom Cruise attended, together with noted German stars such as Katja Riemann or Otto Sander, a commemoration at the Schaubühne in Berlin, honoring his work and life (2 September 2007).
- Shortly before his death, he was awarded honorary citizenship of his hometown Grimma (2007).
- Father of Anna Maria Mühe, together with Jenny Gröllmann.
- Lived in Berlin, Germany.
- Popular reader of audio books.
- Collaborated with author and theatre director Heiner Müller at the Volksbühne and the Deutsches Theater in Berlin, where his 1989 performance as "Hamlet" became legendary.
- Father of five children from three marriages: Andreas (b. November 1979) works a photographer; Konrad Mühe (b. 1982), Anna Maria Mühe (b. 23. July 1985), Sophie Marie (b. 1995) and Jakob (b. 1998).
- Father was a furrier.
- Has an older brother named Andreas, who took over the family furrier business from their father.
- Studied acting at the Theaterhochschule "Hans Otto" in Leipzig in the late 1970s.
- Educated at the Leipzig university for theatre "Hans Otto".
- Even as a child, he dreamed of becoming an actor.
- Ex-stepfather of Jeanne Gröllmann.
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