When Susan Boyle is being photographed, she is carrying her purse in her right hand. She then flips the "bird" with her right hand then the next cut shows her purse back in her right hand.
The Fiat 500 limousine that takes Derek and Hansel to their accommodation in Rome has tinted windows in the distant shots, but clear windows in the close-ups.
When Mugatu maneuvers up the silks, they are wrapped around his waist and one leg. In the next scene, they are only wrapped around his arms.
When the helicopter takes off from Thimble Island fashion prison the tail rotor is not spinning.
Penelope Cruz's mole on her face switches sides throughout the movie.
The boiling kettle in Zoolander's cabin whistles, but doesn't actually have a whistle, just an open spout.