Most of the guns in the game cost more than the properties the player can buy.
When a person in the game is blasted by a shotgun during game play, the wound on that person is that of a bullet wound, and not a buckshot wound. A bullet wound (what is seen) is one small hole with a little blood around it, and a buckshot wound should be seen as a large splatter of blood on the person's body.
Marshall Leigh Johnson in Armadillo says he can't help John arrest Bill since Fort Mercer is in the next county, where he doesn't have jurisdiction. However Johnson is wearing the badge of a Deputy U.S. Marshall, and his bio page also identifies him as being with the U.S. Marshall's Service. The U.S. Marshalls have jurisdiction anywhere in the United States, and prior to the creation of the Bureau of Investigation in 1908 they were the only law enforcement agency with jurisdiction in the Indian Nations. Now if Johnson had been a city marshal or a county sheriff then he would not have jurisdiction in another county.
There is moments when animals gets their 3D models replaced with the human ones for no reason.
The subtitles for the mission "Flowers for a Lady" say "/rWell, that's very sweet of you" for Jack's line. This was fixed in the Game of the Year Edition.
In the mission "Old Friends, New Problems", when Bonnie is greeted, the subtitles say "Howdy, miss", when the man that greets here says "Ma'am". This was fixed in the Game of the Year Edition.