No less than nine writers worked on the script. Besides the credited writers Ted Elliott, Terry Rossio and David S. Goyer, work with also done by James Bonny, Richard Finney, Michael Engelberg, Neal Purvis, Robert Wade and the film's director, 'Stuart Orme. The final version mainly uses ideas from the Goyer and Orme rewrites.
The hive or the Central Intellegence home where everyone gathers to collect intelligence from their human hosts was actually a set built on the Disney lot. While the actual entrance of the nest was at the Los Angeles County Center, with styrofoam walls built there to make it look like it was taken over.
Some shots were filmed in downtown Des Moines, IA.
When the slug has taken over a human, they immediately want to "merge" with one another. The tentacles form the shape of a human hand and interlock themselves with the other slug and stand to transmit information from one host to another and back to the central Hive.
A lot of the scenes involving the meetings with Donald Sutherland and company were actually shot in Fresno, California. Keith David was not exactly thrilled to be working there, stating "It's a good place to pass through, but working...no."