L'olio di Lorenzo

Lorenzo Odone is a regular kid who spent three years in east Africa. Back in the States, he starts having disturbances. It's a mystery that his parents (Nick Nolte, Susan Sarandon) have difficulty solving until he is diagnosed as suffering from ALD. It's a rare incurable degenerative brain disorder that wasn't even identified 10 years before. There are no treatments and he's not expected to survive past 2 years. Then his parents goes all out to research his disease.

This is a perfectly constructed sick-kid-drama. It excels because of the great performances. There is some science but the exposition is simple. And it's impossible not to like the old English scientist with 6 months before retirement. It is heart warming and a tear jerking. It is a great triumph of doggedness and parental love movie.

Definetly one of the most inspiring movies ever made.

As individuals, it would be quite easy to feel helpless while up against a disease such as ALD and a medical establishment that has agendas other than the life of a small child. But Augusto and Michaela Odone refused to just stand idly by and while there son's life slipped away from them. Instead, they made the unprecedented decision to learn as much as they could about their son's devastating illness and then set about to find a cure. Because of their efforts, thousands of boys will now be able to enjoy a life their child will not. Had they not been the exceptionally educated and intelligent people that they were I don't know if they would have been able to accomplish such an unbelievable feat. Who knows? What's important to remember, and what I think is the moral of the story is that great things can be accomplished when people become determined to make a difference.

Though Lorenzo regained his sight, some motor skills, and the ability to swallow, his condition hasn't improved to a large degree over the years, and will not until science is able to regenerate the myelin sheath covering his brain that was all but destroyed by the ALD. At the end of the movie, Augusto was involved with a group of scientists who were about to begin trials that would put the myelin back into some puppies who were born with this defect. I, along with others pray for those suffering from this disorder, as well as for people with other diseases such as Multiple Schlerosis that this therapy could help, that they will be successful.

Sadly, Michaela passed away not too long ago. Being from Virginia the Odone's are considered heros in this state, so her death made the papers here. I cried when I thought of how difficult it must have been for her to have to leave the child she'd spent so many years giving hours upon hours of endless care and attention. I'm sure it never crossed her mind that he would outlive her.

If you've never seen this movie, be sure not to miss it. It's a stellar 10!! But be sure to bring a whole box of tissues, you're going to need it!

This is the true story of Lorenzo Michael Murphy Odone, who, at the age of seven, suffered from a rare, incurable brain disease called ALD. The doctors said there was nothing they could do and that he would die within 24 months of diagnosis. Lorenzo's parents, Augusto Odone (Nick Nolte) and Michaela Odone (Susan Sarandon) decided to gather all the information they could find on their own. Day by day, night by night, from laymen to dedicated researchers, they discovered an awful lot more about the disorder than doctors and scientists. As Lorenzo's condition deteriorated, they never ceased to soldier on. Eventually, Augusto Odone solved the mystery and invented a prescription- a special form of olive oil which could help boys (the disease is passed on by the mothers to their sons, not their daughters) with ALD. Because of his contribution, Odone received an honorary medical degree. And at the age of fourteen, Lorenzo could make some movements and began trying to communicate with the outside world with a computer...

I wept several times when watching this film. Notwithstanding all the odds, the Odones struggled and conquered their misfortune, and their achievement was outstanding. This is an intense drama with fine acting and something to think about deeply.

This Is an excellent movie,great acting,gripping true life story. It is an excellent depiction of the way families sometimes must struggle to win against all odds,even when the majority are saying give up,true "grit",faith carry on. I only wish I would have seen it sooner.

"Lorenzo's Oil" is a movie about the triumph of human spirit and dogged determination. This movie is based on the true story of Michaela and Agusto Odone, whose child Lorenzo was diagnosed with adrenoleukodystrophy (ALD), a degenerative nerve disorder that afflicts only little boys and is always fatal. Michaela and Agusto are determined to find a cure or treatment for this baffling disease while their son slowly and painfully deteriorates. That is the basic premise for the movie, but it is about much more than that.

Michaela and Agusto love their son with unwavering selflessness, and are willing to do anything in their power to save him. This movie is a gripping, touching drama that pulls you in and engulfs you, as finding a cure engulfs the Odones. By the end of the film you will feel a mix of emotions. This movie will give you a newfound respect for the mental and emotional power humans possess.