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A doctor researching "frozen therapy" seeks out Boris Karloff, the therapy's originator. Boris has been missing from his island laboratory for ten years. After ignoring requests to stay off the island by locals, the doctor and his beautiful nurse discover Boris frozen in secret caves beneath the lab. Boris has been frozen along with a host of villagers. Through flashback it is learned these others came to arrest Boris for murder ten years earlier and they all wound up being gassed and frozen. This is the proof Karloff needs to vindicate his research. He sets out to duplicate his accidental results, his methods become increasingly Machiavellian. Ultimately he is his own undoing. This movie is hard to catagorize. The film makers tried to add shock to an interesting scifi story. The film succeeds in spite of the efforts to punch it up. The acting is uneven but overall this is a top notch "B" effort. The science is very plausible, a rarity in old laboratory films. See it and be pleasantly surprised

A doctor (Roger Pryor) studying cryogenics visits the deserted home of Dr. Leon Kravaal (Boris Karloff), a pioneer in the field who went missing ten years before. Uncovering a secret passage in the basement, he and his nurse girlfriend (Jo Ann Sayers) find Kravaal and four other men frozen in ice. They successfully revive Kravaal, who then revives the others. It turns out Kravaal had frozen himself and the others years before when they tried to arrest him. So now the somewhat mad doctor holds them all hostage while he tries to recover his original formula.

Very interesting and entertaining Karloff mad scientist movie. The subject of cryogenics (never called that here, just frozen therapy) is ahead of its time. The rest of the cast is fine but obviously it's Karloff's show the whole way. Intriguing premise with fun execution. A solid "B" movie that's highly enjoyable.

This little known gem from 1940 is impressive for a few reasons: first, it stands head and shoulders above most of the B movies of the era, largely due to a good script and a great performance from Boris Karloff. Also, while made in the midst of the Universal horror period, it demonstrates some of the best elements of that genre, however it also pre-figures the oncoming decade of sci-fi flicks of the 50s, but with a more intelligent, and mysterious, plot than most of the B sci-fi films that followed. It also incorporates some noir elements such as shadowy images, gun play, etc. The Man with Nine Lives is also known under the alternative title Behind the Door (which is actually more accurate).

It's an unusually intelligent storyline for a horror flick. In short, what are the ethical limits to scientific experimentation, even in finding a cure for cancer. Using what is now called "cryogenics", Dr. Kravaal (Karloff) crowds those limits while experimenting with a cancer cure on a remote island. Unfortunately, the promising experiments require live subjects who may not be so lucky. Dr. Mason (Pryor), one of the men trapped on the island with Kravaal, is torn by Kravaal's challenge to conventional ethics. So he's the one we sympathize with as we struggle with the same dilemma-- just how much can be sacrificed in finding a cure.

By no means does Karloff ham up his role. Instead he's perfect as a dedicated and distinguished medical scientist, more obsessed than evil. Except for actor Brown's overdone Adams, the rest of the cast also manages conflicted roles. Credit Columbia for the riveting sets-- for example, the cabin about to be eaten by dead plants, the many dingy underground scenes that really do look subterranean, the laboratory that really looks worked in. All in all, it's an unusually well mounted flick for its subject matter. If there's a problem, it's with the absence of a clear bad guy to heighten a sense of horror amid the dark surroundings. I don't get a sense of menace common to the genre. Instead, the 74-minutes is more like a "think piece", which all in all, may be more worthwhile than a good scare.

It's not exactly a major shock that Boris Karloff plays a mad scientist in this film, though it is very unusual the way he plays this role. Instead of the evil twisted genius set on making monsters or ruling the world, Karloff's goals are incredibly noble. And, when he later kills, you really understand with and could possibly condone why he did this. The moral implications of the film are astounding! As for the rest of the film, the writing for this sort of B-movie is very good, the acting fine and production values work out well (proving you don't need a huge budget to make a good film). About the only negatives at all are the ending (I would have just ended the film a minute or two earlier without the unnecessary final scene) and a mistake in the film about how deep the lab was under the earth. In the beginning, they count 191 steps to the bottom of the shaft to the lab, but later, it's just a homemade ladder about 12 feet long. Regardless, it didn't harm the film in any serious way and the film is a very good 'mad scientist' flick that actually is good entertainment and well thought-out.