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Both the stories are about criminal profiling. Other than that, there is no connection.

No. It's continuous.

The cast have been released from their contracts, because David Fincher will be working on other projects. Officially, it has not been cancelled but even if there is a third season, it won't be produced for a while. In February 2023, David Fincher stated the series is officially done.

"Sectioned" means to have someone committed, preferably to a mental hospital. From Google: Involuntary commitment, civil commitment, or involuntary hospitalization (also known informally as sectioning or being sectioned in some jurisdictions, such as the United Kingdom) is a legal process through which an individual who is deemed by a qualified agent to have symptoms of severe mental disorder is detained... ALSO: 5150 is the number of the section of the Welfare and Institutions Code, which allows a person with a mental illness to be involuntarily detained for a 72-hour psychiatric hospitalization. A person on a 5150 can be held in the psychiatric hospital against their will for up to 72 hours...

Bear in mind that "5150" refers to California law pertaining to a psychiatric hold... Other jurisdictions may use different codes or terminology.

Yes, based on the book "Mindhunter: Inside the FBI's Elite Serial Crime Unit" written by John E. Douglas and Mark Olshaker.