Julianna Margulies

Cites her seven minutes of screen time in the pilot of E.R. - Medici in prima linea (1994) as the turning point in her career. Michael Crichton and Steven Spielberg had been duly impressed with her death scene, as filmed through the eyes of series boyfriend Doug Ross (George Clooney), a decision was made to 'resurrect' her character.

Small gestures can have a big impact. If you walk down the street and smile at someone, that will get passed on to the next person. That has the power to change someone's day.